Fig. 3.
Effect of pretreatment with the δ opioid receptor antagonist NTI on EA-produced inhibition of hyperalgesia and allodynia in a paclitaxel-induced peripheral neuropathy rat model (n=7 per group). EA plus vehicle significantly decreased mechanical response frequency compared to sham EA plus vehicle. NTI pretreatment blocked EA-produced inhibition of hyperalgesia and allodynia. * P<0.05 and ** P<0.01 respectively between vehicle + sham (△) and vehicle + 10 Hz EA (▲); # P<0.05 and ## P<0.01 respectively between NTI + 10 Hz EA (●) vs vehicle + 10 Hz EA (▲).