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. Author manuscript; available in PMC: 2012 Sep 15.
Published in final edited form as: Clin Cancer Res. 2011 Aug 5;17(18):5953–5961. doi: 10.1158/1078-0432.CCR-11-1272

Figure 2.

Figure 2

Inhibitory effect of curcumin on IL-8 expression in the saliva of patients with dental caries. A, The IL-6 expression is less than 5 pg/mL in four of five normal individuals, which is similar to the expression level reported in the literature. Individual #1 has high level expression that could reflect an inflammatory condition. B, IL-8 expression in three individuals resembles the expression range reported in the literature. Individual #3 has three times the expected expression. Appreciable changes were not observed in IL-6 or IL-8 levels after curcumin treatment. C, Of the thirteen patients with dental caries tested, one sample, #11 shows a 50% reduction and another sample #3 has a four-fold increased expression of IL-6. Appreciable changes are not seen in other samples. D, Eight of the dental caries patients show reduced IL-8 expression and four of them show greater than 25% reduction (#1, 3, 11 and 13). One sample, #8, shows a 20% increase in IL-8 expression post curcumin treatment.