Table 4.
Multivariate analysis by stepwise logistic regression to assess independent risk factors associated with poor response to treatment, progression to ESRD or death and renal flares (relapses) in patients with Class III and IV (proliferative) lupus nephritis
| Response | Risk Factor | Regression coefficient |
P-value | Odds ratio |
Lower95% CL |
Upper 95% CL |
|---|---|---|---|---|---|---|
| No response | Mycophenolate as maintenance agent | −0.927 | 0.045 | 0.396 | 0.160 | 0.979 |
| Chronicity index | 0.558 | 0.001 | 1.747 | 1.246 | 2.450 | |
| ESRD or Death | Hypertension | 1.691 | 0.042 | 5.425 | 1.066 | 27.612 |
| Chronicity index | 0.572 | 0.0007 | 1.771 | 1.273 | 2.464 | |
| Relapses | Hypertension | 2.334 | 0.027 | 10.322 | 1.310 | 81.308 |