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. Author manuscript; available in PMC: 2012 Sep 16.
Published in final edited form as: ACS Chem Biol. 2011 Jul 20;6(9):952–961. doi: 10.1021/cb200205z

Figure 5.

Figure 5

DMH1 does not ablate single cell migration. a) Epicardial cells cultured in medium have minimal single cell migration in Boyden chamber assays. b,d) Single cell migration is significantly enhanced by stimulation with TGFβ1. c,d) TGFβ1 stimulation was inhibited by DM/LDN-193189 to a migration rate equivalent with medium, (p=0.056). d) TGFβ1 stimulation was only marginally inhibited by DMH1, unlike the TGFβ inhibitor SB-431542, which ablated this behavior. [n=30 images; (*p<0.001 from TGFβ1 ~p<0.001 from SFM)].