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. 2011 Aug 28;2(3):163–174. doi: 10.1007/s13539-011-0039-1

Table 2.

The effects of 30 mg/kg BL-6020/979 p.o. on gene expression in the C26 tumor model

Group Atrogin-1 PGC-1β
Vehicle 1.0 (0.9–1.2)*** 1.1 (0.8–1.2)***
Vehicle + tumor 20.1 (4.1–28.8) 0.2 (0.1–0.4)
30 mg/kg BL-6020/979 + tumor 3.0 (1.4–19.4) 0.5 (0.2–0.6)***

Relative expression levels of Atrogin-1 and PGC-1β in gastrocnemius muscle of mice. Median (interquartile range) are given (n = 27–29/group). Statistical difference in Dunn’s post hoc test vs. Vehicle + tumor with ***p < 0.001