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. 2011 Sep 21;101(6):1326–1334. doi: 10.1016/j.bpj.2011.08.004

Figure 1.

Figure 1

Channelrhodopsin-2 (ChR2) is a light-gated cation channel native to the green alga C. reinhardtii. It consists of seven transmembrane proteins and absorbs light through its interaction with retinal. Here, we induce channelrhodopsin coupled to enhanced yellow fluorescent protein (eYFP) into undifferentiated human embryonic stem cells via a lentiviral vector and differentiate these cells into cardiomyocytes.