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. Author manuscript; available in PMC: 2012 Sep 1.
Published in final edited form as: J Pediatr Surg. 2011 Sep;46(9):1711–1719. doi: 10.1016/j.jpedsurg.2011.01.023

Table 1.

Relative efficiencies of generating mutant embryos with Hprt-Cre vs. Traditional heterozygous null/+ breedings

Breeding Normal (n) Mutant (n) % Mutants Litters Embryos/litter(n)
Fgfr2IIIbrec/+; HprtCre/+ X Fgfr2IIIb flox/flox 81 85 51.20% 18 9.22
Fgfr2IIIbnull/+ X Fgfr2IIIbnull/+ 129 38 22.75% 18 9.28