Table 1.
Body and kidney weight, plasma estradiol and blood pressure
Intact | OVX | OVX+E2 | ||||
---|---|---|---|---|---|---|
4M | 12M | 4M | 12M | 4M | 12M | |
Body weight (g) | 262.5±9.4 | 377.7±17.9** | 317.3±5.2# | 421.0±18.0**,## | 228.3±2.3#,§§§ | 285.8±9.3*,###,§ |
Kidney weight (g) | 0.88±0.02 | 1.11±0.04 | 0.83±0.02 | 1.03±0.04 | 0.93±0.03 | 1.4±0.11*,#,§§ |
Kidney/body weight (mg/g) | 3.4±0.09 | 3.0±0.16 | 2.6±0.06# | 2.5±0.15 | 4.1±0.12#,§§ | 3.6±0.15#,§§ |
Plasma estradiol (pg/ml) | 38.1±9.4 | 5.5±1.3* | 12.7±1.5# | 6.6±1.5## | 32.5±2.4§ | 19.4±2.6*,#,§ |
MAP (mmHg) | 120.6±7.6 | 150.8±8.6* | 127.7±4.6 | 167.3±5.5**,# | 115.1±2.0 | 122.5±6.2*,#,§ |
Data are expressed as mean ± SEM.
P<0.05,
P<0.01 vs. 4M in the same treatment group
P<0.05,
P<0.01,
P<0.001 vs. Intact in the same age group
P<0.05,
P<0.01,
P<0.001 vs. OVX in the same age group