Table 1.

Interactions between thrombin and mTBA at the most extended interface

mTBA residue	Hydrogen bonds				Hydrophobic interaction
	Atom	Thrombin residue	Atom	Distance (Å)	Thrombin residue
Gua2	O2P	Arg77A	NH1, NH2	3.17, 3.27
Thy3	–	–	–	–	Tyr76, Leu65, Ile82
Thy4	O4′	Tyr76	N	2.83	Tyr76
Thy4	O2	Arg75	NH2	3.07
Thy4	O4	Arg77A	NH1	2.90
Thy12	N3	Glu77	OE2	2.88	Ile79
Thy13	O4	Arg75	NH1, NH2	3.15, 2.57	Asn78, Ile79
Thy13	O3′	Asn78	ND2	2.81