Fig. 6.
Expression profiles of TH immunoreactivity in the LC of MAO A KO (day 30 and 150) and WT (day 30) mice. Note the rather similar intensity profiles of TH immunreactivity among the three groups of animals in A2, B2, and C2. High power views of individual TH immunoreactive LC neurons are shown in A3, B3, and C3. The intensity and spatial distribution profiles of TH immunoreactive dendrites (pointed by two white arrows in A3, B3, and C3) are shown in A4, B4, and C4. Yellow arrows represent the “beaded appearance” profiles in B3, C3, B4, and C4. Notice especially the beaded appearance of dendrites in MAO A KO mice at day 30 (B4) compared to day 150 (C4). In contrast, rather smooth dendrites are often found in WT (A4). Scale bar in C1 applies to A1 and A2 rows. Scale bar in C3 applies to A3 row. Scale bar in C4 applies to A4 row.