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. Author manuscript; available in PMC: 2011 Sep 21.
Published in final edited form as: Bioorg Med Chem Lett. 2008 Sep 11;18(20):5443–5447. doi: 10.1016/j.bmcl.2008.09.032

Figure 2.

Figure 2

10 μM compound screen for M1 activation. Data represent the mean±SEM of three independent determinations with TBPB (1), ACh and CCh as positivie controls. Boxed panels show the sulfonyl chlorides 7a–7k and isocyanates 8a–8r employed in the library (Scheme 2).