Table 3.
Results from neurocognitive tests by history of severe hypoglycemia
| Type 1 diabetes |
Cohen d effect size (early severe hypoglycemia vs. control) | |||
|---|---|---|---|---|
| Early severe hypoglycemia (before 6 years) | Late severe hypoglycemia (after 6 years) | No history of severe hypoglycemia | ||
| Sample size | 6 | 14 | 13 | |
| Age (years) | 20.7 ± 1.5 | 19.3 ± 0.6 | 18.6 ± 0.6 | |
| WISC-IV and WAIC-IV | ||||
| Full-scale IQ | 95.2 ± 4.3 | 103.3 ± 2.6 | 100.5 ± 3.7 | −0.74 |
| Verbal comprehension index | 93.5 ± 3.8 | 102.1 ± 2.3 | 102.2 ± 4.5 | −0.65 |
| Perceptual reasoning index | 97.8 ± 4.8 | 103.9 ± 3.1 | 97.6 ± 3.0 | −0.41 |
| Working memory index | 91.5 ± 5.1 | 102.9 ± 2.9 | 103.0 ± 4.4 | −0.80 |
| Processing speed index | 103.0 ± 3.5 | 100.9 ± 3.2 | 100.2 ± 4.4 | −0.14 |
| WMS-IV | ||||
| Auditory memory index | 101.7 ± 6.5 | 107.4 ± 3.9 | 97.8 ± 5.4 | −0.11 |
| Immediate memory index | 100.7 ± 9.1 | 105.2 ± 4.6 | 96.5 ± 4.2 | −0.09 |
| Delayed memory index | 97.0 ± 9.5 | 103.3 ± 3.7 | 97.5 ± 5.8 | −0.40 |
| CCFIT | ||||
| CCFIT IQ | 107.5 ± 8.1 | 111.9 ± 4.9 | 107.9 ± 3.8 | −0.66 |
| WCST | ||||
| Perseverative error | 24.8 ± 5.8 | 18.6 ± 2.8 | 17.15 ± 3.6 | 1.26 |
| Completed categories | 3.2 ± 0.8 | 5.0 ± 0.3 | 5.6 ± 0.2 | −1.71 |
Data are mean ± SE.