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Viral regulation of RLR signaling. The RLR signalsome is shown including the RNA polymerase/RIG-I pathway for indirect recognition of cytosolic foreign DNA. Viral proteins known to block RLR signaling are shown with lines associating the specific factors they target. viruses or viral genus are denoted in parenthesis next to their specific proteins. Abbreviations: CCHFV (Crimean Congo Hemorrhagic Fever virus), BDV (Borna Disease virus), HTNV (Haantan virus).
