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. Author manuscript; available in PMC: 2011 Sep 21.
Published in final edited form as: J Mol Cell Cardiol. 2009 Mar 2;46(6):832–841. doi: 10.1016/j.yjmcc.2009.02.018

Figure 3.

Figure 3

Simulations as conducted in Figure 2 but with and without the addition of a creatine kinase equilibrium reaction. After each step in ATP hydrolysis (2% hydrolysis steps), the creatine kinase reaction was permitted to reach equilibrium through a numerical approximation. The creatine kinase equilibrium constant was assumed to be 1.66×109. pH was 7.0. Other parameters were identical to those in Figure 2. A) Plot of ATP and the ΔGATP with, solid line, and without the creatine kinase reaction, dotted line. B) Plot of ADP and Pi with, solid line, and without the creatine kinase reaction, dotted line.