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. 2011 Sep 21;6(9):e25269. doi: 10.1371/journal.pone.0025269

Figure 7. ALIOS-fed mice treated with liraglutide confirm GLP-1 enhanced lipoautophagy in liver.

Figure 7

(A). Immunoblot comparing beclin, LC3B conversion and LAMP2 levels in liver lysates from mice treated with liraglutide or ALIOS diet or combination thereof. (B) Quantification of immunoblot by densitometry. Differences between protein levels were significant for respective genes between ALIOS and ALIOS+Liraglutide samples (C) Real time PCR analysis of Beclin, LC3B and LAMP2 gene expression. Histogram shows fold change in ALIOS-fed, liraglutide treated animals versus ALIOS fed animals. These experiments were performed with lysates from six mice, *p<0.05 Student's t-test.