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. 2011 Sep 21;6(9):e25324. doi: 10.1371/journal.pone.0025324

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Ding et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Rats were subjected to 60 min MCAO and 24 hour reperfusion. The expression of FPN1 in the cerebral cortex (A), hippocampus (B) and corpus striatum (C) of contralateral and ipsilateral side was analyzed by Western blotting. Representative bands from contralateral side and ipsilateral side are shown on the top panel. The lower panel (D) shows the summary of FPN1 expression from three animals in each group. The expression of FPN1 was very significantly increased in the ischemic cerebral cortex, corpus striatum at 24 h, and was significantly increased in the ischemic hippocampus at 24 h. Results are presented as Mean ± SEM, n = 3. **p<0.01 v.s. contraleteral side, *p<0.05 v.s. contralateral side.