Fig. 3.

a Composite fundus photograph of the left eye of patient V-4, of family 1 with a c.3317dup (p.Ser1107ValfsX4) mutation in the RPGR ORF15 gene, performed at age 27 years. No macular abnormalities are apparent yet. b Composite fundus photograph of the left eye of patient IV-19 of family 1 with the c.3317dup (p.Ser1107ValfsX4) mutation in RPGR ORF15, performed at age 71 years. The retina shows retinal pigment epithelium atrophy in the macular region and peripapillary atrophy. The patient has high myopia