Table 2.

Statistical analysis (dichotomization in no leukoaraiosis + mild leukoaraiosis versus moderate leukoaraiosis + severe leukoaraiosis).

UNIVARIATE ANALYSIS, ME, SISCO, AND MMS DICHOTOMIZED ACCORDING TO SAMPLE MEDIAN
Original variable	Median	p-Value$	OR	95% CI for OR
ME	16	<0.0005	0.05	(0.01, 0.38)
SISCO	50	0.001	0.05	(0.01, 0.41)
MMS	28	0.008	0.16	(0.04, 0.65)
Hyperlipidemia		0.020	0.19	(0.05, 0.77)
MULTIVARIATE ANALYSIS USING FORWARD SELECTION (WALD-TEST)
Variable		p-Value wald-test	OR	95% CI OR
Model 1
Age		0.500	0.97	(0.90, 1.05)
ME		0.005	0.03	(0.003, 0.36)
Hyperlipidemia		0.030	0.17	(0.03, 0.84)
Model 2
Age		0.439	0.97	(0.90, 1.05)
SISCO		0.003	0.02	(0.002, 0.28)
Hyperlipidemia		0.007	0.10	(0.02, 0.52)

^$p-Values from Fisher’s exact test.

CI, Confidence Interval; OR, Odds Ratio.