Table 3.
Relative changes in insulin-exposed Runx2-null cells (insulin/control) | |||||||
---|---|---|---|---|---|---|---|
receptors | transducers | transcription factors | target genes | ||||
IR | 20% | IRS1 | 30% | C/EBPα | NC | Glut4 | NC |
IGF1R | 50% | CAP1 | 30% | Srebf1 | 70% | Adiponectin | NC |
LDLR | 20% | Rras2 | 50% | PPARγ | NC | Leptin | 60% |