Figure 4 .

Plot of the proportion of male progeny of the cross as a function of the alleles at the two major sex-determining loci in zebrafish. The B allele of chromosome 5 (originating from the IN strain male grandparent) corresponds to the male-associated allele of dmrt1, here marked by ss48808156 (T variant of the A/T SNP) in the cross. The A allele of chromosome 16 (originating from the AB strain female grandparent) corresponds to the male-associated allele of cyp21a2, here marked by ss48940970 (T variant of the T/C SNP) in the cross. The 95% confidence intervals of the proportion of males among zebrafish with a given two-locus genotype are illustrated for each data point.