Figure 5.

Improvement of limbal hypertrophy, corneal punctate epithelial erosions, corneal pannus and corneal stromal opacity after treatment with topical 0.005% tacrolimus eye drop in refractory VKC. In this eye with conjunctival hyperaemia and limbal hypertrophy (a), there was significant improvement after treatment (b). Another eye with diffuse corneal punctate epithelial erosions (c) showed smooth corneal surface with no erosion after treatment (d). In this eye with severe conjunctival hyperaemia and corneal pannus formation (e), hyperaemia and corneal pannus decreased after treatment (f). In this eye with active VKC and corneal stromal opacity (g), there was decreased corneal stromal opacity after treatment with increased BSCVA from 20/200 to 20/70 (h).