Table 1. Characteristics of patients and eyes with culture or smear positive acanthamoeba keratitis.
| Repeated cultures/smear (N=15) | Single culture/smear (N=17) | P-valuea | |
|---|---|---|---|
| Age, years (mean (range)) | 43.7 (15–87) | 33.5 (13–59) | 0.08 |
| Female (N, (%)) | 9 (60%) | 12 (71%) | 0.71 |
| Presenting visual acuity (median (IQR)) | 20/70 (20/50 to CF) | 20/70 (20/30 to 20/200) | 0.37 |
| 6-month visual acuityb (median (IQR)) | CF (20/125 to HM) | 20/25 (20/20 to 20/40) | 0.0003 |
| Duration of symptoms prior to presentation, days (median (IQR)) | 30 (14, 56) | 23 (17, 30) | 0.66 |
| Use of steroids at presentation (%) | 12 (80) | 14 (82) | 1.0 |
| Stromal involvement (%) | 13 (86.7) | 13 (76.5) | 0.66 |
| Penetrating keratoplasty (%) | 5 (35.7) | 0 | 0.01 |
| Monotherapy (%) | 4 (26.7) | 8 (47.1) | 0.29 |
Abbreviations: N, number of patients (each patient had unilateral disease); CF, counting fingers; HM, hand motions; IQR, interquartile range.
a
Rank-sum test for continuous variables, and Fisher's exact test for categorical variables.
b
Defined as visual acuity closest to the 6-month visit after presentation.