TABLE 1.

Metabolic parameters after 12 weeks of HFD

Genotype	ArntF/F	Arnt∆Adipo	Hif1aF/F	Hif1α∆Adipo
Fasting glucose (mg/dL)	150 ± 21.7	106 ± 21.5*	172 ± 32.5	131 ± 19.8*
Fed glucose (mg/dL)	269 ± 28.1	139 ± 27.9†	206 ± 23.5	149 ± 30.4†
Fasting serum insulin (ng/mL)	3.6 ± 1.4	2.1 ± 0.8*	2.6 ± 0.6	1.1 ± 0.2†
HOMA index	31.7 ± 8.6	13.8 ± 7.6†	27.9 ± 10.4	8.4 ± 1.8†
Fasted serum triglyceride (mg/dL)	124 ± 42.1	78.4 ± 7.5*	162 ± 38.8	99.4 ± 19.8†
Fasted serum cholesterol (mg/dL)	182 ± 37.6	169 ± 43.6	196 ± 45.8	160 ± 24.1
Fasted serum FFA (mmol/L)	1.88 ± 0.42	1.07 ± 0.39*	1.63 ± 0.35	1.09 ± 0.30*

Data are means ± SD.

*P < 0.05.

†P < 0.01 compared with controls.