TABLE 1.

Metabolic characteristics of wild-type and Id1^−/− mice fed a chow or a high-fat diet for 6 weeks

	Wild-type		Id1−/−
	Chow (n = 8–19)	Fat (n = 7–16)	Chow (n = 7–22)	Fat (n = 6–14)
Blood glucose (mmol/L)	8.2 ± 0.3	9.0 ± 0.4	7.5 ± 0.3	8.1 ± 0.3
Blood insulin (ng/mL)	0.31 ± 0.04	0.68 ± 0.05***	0.38 ± 0.04	0.66 ± 0.09**
HOMA-IR	2.8 ± 0.4	6.9 ± 0.6***	3.3 ± 0.5	6.6 ± 1.0***
Plasma glucagon (pg/mL)	54.0 ± 8.5	50.7 ± 7.9	50.8 ± 9.7	64.4 ± 8.4
Plasma triglyceride (mmol/L)	1.37 ± 0.07	1.97 ± 0.15*	1.34 ± 0.11	2.03 ± 0.25*
Plasma NEFA (mmol/L)	0.23 ± 0.02	0.30 ± 0.03	0.25 ± 0.02	0.27 ± 0.01

Values are means ± SEM.

*P < 0.05,

**P < 0.01, and

***P < 0.001 for effect of diet in wild-type and Id1^−/− mice.