FIG. 8.

Lipid contents of liver and skeletal muscle after 3 days of HFD. Eighteen-week-old C57BL6J male chow-fed mice were started in 60% HFD at day 0 for 3 days before the analyses. A separate group of age-matched chow-fed mice was studied as controls. For the macrophage depletion experiment, two shots of clodronate injection (100 mg/kg i.p.) were given at day −3 and 0. Veh, vehicle; Clod, clodronate-liposomes; TG, triacylglyceride; NS, not significant. A: Lipid contents in liver. B: Lipid contents in skeletal muscle. n = 8. *P < 0.05; **P < 0.01.