Table 2. Breast experiment 1 and 2.
Results from manual scoring [median (IQR)] of immunostaining in stroma, glandular epithelium (GE) and ductal epithelium (DE).
| Stroma 1 | OvxC | CEE | CEE+MPA | MPA | TAM | Stroma 2 | OvxC | CEE | CEE+MPA | TIB |
|---|---|---|---|---|---|---|---|---|---|---|
|
COX-1 p=0.361 |
2 (2-2.75) | 2 (2-3) | 1 (1-2.75) | 2 (1-3) | 2 (2-3) |
COX-1 p=0.845 |
2 (1.25-2) | 2 (1-2) | 2 (1-2.75) | 2 (2-2) |
|
COX-2 p=0.200 |
1 (1-1) | 1 (1-2) | 1 (1-1) | 1 (0.25-1) | 1 (0-1) |
COX-2 p=0.519 |
0 (0-0) | 0 (0-0) | 0 (0-0) | 0 (0-0) |
| GE 1 | OvxC | CEE | CEE+MPA | MPA | TAM | GE 2 | OvxC | CEE | CEE+MPA | TIB |
|
COX-1 p=0.012 |
1 (1-2) | 1 (1-2) | 1 (0-1) | 2 (1-3)c ▲ |
2 (1-2.75)c ▲ |
COX-1 p=0.075 |
1 (1-2) | 1 (1-3) | 1 (1-1) | 1 (1-2) |
|
COX-2 p=0.197 |
3 (3-3) | 3 (2-3) | 3 (2-3) | 3 (3-3) | 3 (2-3) |
COX-2 p=0.016 |
1 (1-1.75) | 2 (2-2.75)a ▲ |
2 (1-2) | 2 (1-3) |
| DE 1 | OvxC | CEE | CEE+MPA | MPA | TAM | DE 1 | OvxC | CEE | CEE+MPA | TIB |
|
COX-1 p=0.002 |
2 (1-3) | 2 (1-3) | 1 (0-1)a ▼ |
2 (2-3)c ▲ |
2 (1-2.75) |
COX-1 p=0.067 |
2 (1-2) | 2 (1-3) | 1 (1-1.75) | 1 (1-2) |
|
COX-2 p=0.265 |
3 (3-3) | 3 (3-3) | 3 (2-3) | 3 (3-3) | 3 (2-3) |
COX-2 p=0.109 |
1.5 (1-2) | 2 (1.75-2.25) | 2 (1.5-2) | 2 (2-3) |
a
= statistically significant from OvxC
c
= statistically significant from CEE+MPA.