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. Author manuscript; available in PMC: 2011 Sep 22.
Published in final edited form as: Dev Biol. 2008 Apr 25;319(2):248–257. doi: 10.1016/j.ydbio.2008.04.019

Figure 1.

Figure 1

Prospective pituitary precursors express deltaA and notch1a after the 10-somite (14h) stage

Wild-type embryos doubly labeled with mRNA probes for cathepsin L,1b (ctsl1b), previously known as hatching gland gene 1(hgg1;A–F, red) and pitx3 (A,B), deltaA (C,D), or notch1a (E,F). (A,C,E) At Bud stage, presumptive pituitary precursor cells express pitx3 (A, n = 25; dotted lines indicate approximate location according to Dutta et al., 2005). deltaA (C, n=30) and notch1a (E, n=30) are not expressed in pituitary precursors. At 10-somite stage (14h), anterior cranial placode precursors (arrowheads) express pitx3 (B, n=25), deltaA (D, n=25), and notch1a (F, n=25). (A,C,E) Dorsal views, anterior to the top (dotted lines indicate approximate location of pituitary precursor cells according to Dutta et al., 2005); (B,D,F) dorsal views of prospective head region, anterior to the top. Scale bar: 50 µm.