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Effects of anti-SP-R210 on M. tuberculosis-induced cytokine secretion. PBMC from 12 PPD+ donors were incubated in the presence or absence of different IgG (10 μg/ml) as indicated, together with 2.5 μg/ml heat-killed M. tuberculosis. After 48 h incubation, the culture supernatants were collected, and concentrations of IFN-γ (A), TNF-α (B), and IL-10 (C) were measured by sandwich ELISA. Mean values ± se are shown for each cytokine.
