Table 2. Profile summaries for selected CBMs containing aromatic residues conserved to known ligand-binding residues.

Family	UniProt	Protein	Position	Organism	HARs	Template(s)	Identity	Z score
CBM4	Q59218	Arabinosidase	59–197	Bacteroides ovatus	W76, Y79, F116, F117	2zex	26.9	–0.463
CBM6	P77847	β-1,4-mannanase	453–575	Caldocellum saccharolyticum	W461, Y472, Y477, F481, Y499, Y514, W520, F538, Y564	1w9s–1uxx	27.9	–0.454
CBM32	Q8IK83	LCCL domain-containing protein	305–420	Plasmodium falciparum	Y307, Y329, W330, F335, Y339, F380	2j1v–2j7m	26.7	–0.510
CBM53	A4F2M4	Starch synthase III	280–365	Phaseolus vulgaris	F306, W309, F314, W327, F346, Y352	2v8l–2c3w	24.3	–0.367

The italics denote aromatic residues conserved to reported ligand-binding residues in corresponding template(s). No experimental data concerning their ligand-binding abilities is available for the unannotated HARs. The used template structures are 2zex [44], 1w9s [45], 1uxx [46], 2j1v [24], 2j7m [47] and 2v8l [48], 2c3w [49].