Table 3. Occurrence times for residues that flank known ligand-binding aromatic residues.

G	N	S	T	D	A	Q	I	E	K	V	L	Y	P	C	M	F	H	R	W
49	43	34	34	33	30	27	22	22	20	16	13	9	8	6	6	6	4	3	3

The occurrence times were derived from the two upstream and downstream residues flanking 97 known aromatic ligand-binding residues and were transformed into weighted scores for HAR prediction.