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. 2011 Sep 22;7(9):e1002294. doi: 10.1371/journal.pgen.1002294

Table 1. Effects of deletion of 1α(OH)ase or PTH on serum biochemistries in CaR−/− mice.

WT CaR−/− 1α(OH)ase−/− CaR−/−1α(OH)ase−/−
Serum calcium (mmol/L) 2.7±0.07 3.9±0.22*** 2.4±0.05* 2.6±0.08###
Serum phosphorus (mmol/L) 3.3±0.14 1.4±0.20*** 2.7±0.18* 1.0±0.05*** ##
Serum ALP (IU/L) 304±55.5 1880±203*** 461±15.3* 2240±44.1*** #
Serum PTH (pg/ml) 18.4±5.02 311±11.4*** 28.1±3.34* 492±30.2*** ##
Serum 1,25(OH)2D3 (pg/ml) 158±12.3 314±32.5*** 0 0

*, P<0.05;

**, P<0.01;

***, P<0.001 compared with wild-type mice;

#, P<0.05;

##, P<0.01;

###, P<0.001 compared with CaR−/− mice.