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. 2011 Sep 22;6(9):e25271. doi: 10.1371/journal.pone.0025271

Figure 2. GW501516 suppresses interstitial inflammation in a protein-overload mouse renal injury model.

Figure 2

(A) Representative photomicrographs of F4/80 immunostaining of the kidney from four groups [PBS(−), PBS(−) + GW501516, Protein-overload and Protein-overload + GW501516] (magnification, upper: ×100, lower: ×400). Renal mRNA expression of F4/80 (B), MCP-1 (C), TNFα (D) and IL-6 (E) in kidney samples from the four groups. Data are shown as means ± SEM. Results are expressed as the fold change relative to the mean value of the mRNA expression level of the PBS(−) group. MCP-1: monocyte chemoattractant protein-1; TNFα: tumor necrotic factor α.