Figure 1. Abnormal respiration activity in Bmal1 -/- mice.

(A) The respiratory quotient (RQ) of male mice housed under the light/dark condition (LD) or constant darkness condition (DD) was determined by indirect calorimeter. The daily average of RQ corrected by body weight was calculated. Data represent the means ± SEM (n = 6 for each genotype). Asterisks indicate significant differences (P<0.05).