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. 2011 Sep 22;6(9):e25231. doi: 10.1371/journal.pone.0025231

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Shimba et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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All tissue samples were excised at ZT10. (A) Representative morphology of the livers from control mice and Bmal1 -/- mice fed a HFD for 5 weeks. (B) Representative oil red O staining of liver tissue samples isolated from male control mice and Bmal1 -/- mice fed either a RD or HFD for 5 weeks. (C and D) Triglyceride (TG) contents in the liver (C) and skeletal muscle (D) from male control mice and Bmal1 -/- mice fed a RD or HFD for 5 weeks. Data represent the means ± SEM (n = 8 for each genotype and treatment). Asterisks indicate significant differences (P<0.05).