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. 2011 Sep 22;6(9):e25231. doi: 10.1371/journal.pone.0025231

Table 1. Content of cholesterol and triglycerides in lipoproteins.

Cholesterol (mg/dL) Triglyceride (mg/dL)
CM VLDL LDL HDL CM VLDL LDL HDL
RD Control 0.1±0.0 2.9±0.2 11.1±0.1 59.4±5.8 0.6±0.1 15.6±1.4 9.5±1.1 1.7±0.2
Bmal1-/- 0.3±0.0* 7.3±0.8* 20.5±0.3* 35.2±4.8* 4.6±0.5* 19.4±2.1 12.7±1.4* 2.3±0.2*
HFD Control 0.2±0.0 5.7±0.6 25.9±3.8 123.2±20 3.5±0.4 18.8±1.9 6.5±0.7 1.8±0.1
Bmal1-/- 0.3±0.0 8.3±1.0* 128.2±14* 184.7±23* 5.3±0.6* 9.1±1.1* 14.9±1.8* 3.4±0.4*

Blood samples were collected at ZT 10. Plasma samples were prepared from male control mice and Bmal1 -/- mice fed either a regular diet (RD) or a high fat diet (HFD) for 5 weeks. Plasma lipoproteins were separated and analyzed by an on-line dual enzymatic method for simultaneous quantification of cholesterol and triglycerides by HPLC. Data represent the means ± SEM (n = 5 for each genotype). Asterisks indicate significant differences (P<0.05).