Table 3. Peroxisomal proteins from different organisms representing the major eukaryotic groups and their predicted targeting signals.
eukaroytic group | organism | Pex7 | 3-ketoacyl-CoA thiolase | acyl-CoA oxidase | citrate synthase | malate dehydrogenase |
Chromalveolata | Phaeodactylum tricornutum | — | PTS1 | PTS1 | x | x |
Thalassiosira pseudonana | — | PTS1 | PTS1 | x | PTS1 | |
Fragilariopsis cylindrus | — | PTS1 | PTS1 | x | x | |
Ectocarpus siliculosus | yes | PTS2 | x | x | x | |
Phytophthora infestans T30-4 | yes | PTS2 | PTS2 | x | PTS1 | |
Perkinsus marinus | yes | PTS2 | PTS1 | x | x | |
Tetrahymena thermophila | yes | PTS2 | PTS2 | PTS1, PTS2 | PTS2 | |
Plantae | Cyanidioschyzon merolae | — | PTS1a | PTS1 | PTS1 | x |
Chlamydomonas reinhardtii | yes | PTS2 | PTS1 | PTS2 | PTS2 | |
Volvox carteri | yes | PTS2 | PTS2 | PTS2 | PTS2 | |
Physcomitrella patens | yes | PTS2 | PTS1 | PTS1, PTS2 | PTS2 | |
Arabidopsis thaliana | yes | PTS2 | PTS1, PTS2 | PTS1, PTS2 | PTS2 | |
Excavata | Naegleria gruberi | yes | PTS1 | PTS2 | x | x |
Unikonta | Trichoplax adhaerens | yes | PTS2 | PTS1 | x | x |
Dictyostelium discoideum | yes | PTS2 | PTS1, PTS2 | PTS2 | PTS2 | |
Saccharomyces cerevisiae | yes | PTS2 | b | PTS1 | PTS1 | |
Ustilago maydis | yes | PTS2 | PTS1 | x | x | |
Caenorhabditis elegans | — | PTS1 | PTS1 | PTS1 | x | |
Danio rerio | yes | PTS2 | PTS1 | x | x | |
Mus musculus | yes | PTS2 | PTS1 | x | x | |
Rattus norvegicus | yes | PTS2 | PTS1 | x | x |
possible unkown derivat AAL of the conventional PTS1 consensus sequence.
the peroxisomal acyl-CoA oxidase of S. cerevisiae lacks both PTS1 and PTS2 targeting signal [60].
It should be noted that currently no genome data of a rhizarian organism is available. PTS1, peroxisomal targeting signal 1; PTS2, peroxisomal targeting signal 2; x, no peroxisomal orthologs identified; —, no orthologs identified.