Table 5.

Rate ratio (RR) of seminoma and non-seminoma testicular cancer according to familial testicular cancer by type of testicular cancer and type of relative.

	seminoma testicular cancer			non-seminoma testicular cancer
Cancer Site (ICD-7)	nca/nco	RR (95% CI)	p	nca/nco	RR (95% CI)	p
All Seminomasa	17/4	9.10(3.05–27.13)	<0.0001	20/6	9.63(3.27–28.37)	<0.0001
Seminoma, fatherb	8/3	5.35 (1.42–20.18)	0.01	9/4	4.51(1.39–14.63)	0.01
Seminoma, brotherc	5/0	- -	-	10/2e	- -	-
Seminoma, sond	4/1	8.73(0.97–78.26)	0.05	1/0	- -	-
All Non-seminomaa	22/9	5.23 (2.40–11.36)	<0.0001	10/7	2.97 (1.13–7.82)	0.03
Non-seminoma, fatherb	8/3	5.33(1.42–20.08)	0.01	5/3	3.33(0.80–13.92)	0.10
Non-seminoma, brotherc	12/5	5.27(1.85–15.02)	0.002	5/3	3.48(0.83–14.58)	0.09
Non-seminoma, sond	2/1	4.18 (0.38–46.06)	0.24	0/1	- -	-

n_ca: number of cases with the particular cancer in the family

n_co: number of controls with the particular cancer in the family

p: P-value

RR: rate ratio

95 % CI: 95 percent confidence interval

^aadjusted for number of known male first-degree relatives

^badjusted for identification of father or not

^cadjusted for number of known brothers

^dadjusted for number of known sons

^eboth controls with a brother having seminoma testicular cancer were matched with a case also having an affected brother, consequently no estimates could be obtained.