Table 5.
Multivariable predictors of all cause mortality among the subjects who received either combined chemoradiation therapy or no adjuvant therapya.
| Covariate | Hazard Ratio (95% CI) | p-value | |
|---|---|---|---|
| Treatment | |||
| No adjuvant therapy | 1.0 | --- | |
| Chemotherapy and radiation therapy | 0.90 (0.72, 1.12) | 0.3453 | |
| Age at diagnosis (per year increase) | 1.03 (1.01, 1.04) | 0.0002 | |
| Gender | |||
| Male | 1.02 (0.85, 1.23) | 0.8396 | |
| Female | 1.0 | --- | |
| Race | |||
| White | 1.0 | --- | |
| Asian | 0.73 (0.54, 0.97) | 0.0327 | |
| Other (including black) | 1.13 (0.84, 1.53) | 0.4243 | |
| SES Quintile (per quintile increase) | 1.00 (0.93, 1.06) | 0.9277 | |
| Six month diagnosis block (per block increase) | 0.97 (0.92, 1.03) | 0.3190 | |
| T category | |||
| T1 | 1.0 | --- | |
| T2 | 1.27 (0.81, 1.98) | 0.3023 | |
| T3 orT4 | 1.60 (1.01, 2.55) | 0.0472 | |
| N category | |||
| N0 | 1.0 | --- | |
| N1 | 2.04 (1.62, 2.57) | <0.0001 | |
| N2 | 3.48 (2.62, 4.63) | <0.0001 | |
| N3 | 3.73 (2.38, 5.84) | <0.0001 | |
| Grade | |||
| 1 | 1.0 | --- | |
| 2 | 1.44 (0.75, 2.75) | 0.2720 | |
| 3/4 | 1.98 (1.05, 3.75) | 0.0355 | |
| Charlson comorbidity score (per score increase) | 1.08 (1.00, 1.16) | 0.0411 | |
| Gastrectomy at teaching hospital | |||
| Yes | 0.90 (0.74, 1.08) | 0.2555 | |
| No | 1.0 | --- | |
| Distance to RT facility (per additional mile) | 1.00 (1.00, 1.00) | 0.9661 | |
| SEER Region | |||
| Northeast | 0.96 (0.76, 1.22) | 0.7536 | |
| South | 1.18 (0.89, 1.59) | 0.2548 | |
| Midwest | 1.15 (0.83, 1.58) | 0.3984 | |
| West | 1.0 | --- | |
Model n=809.
Abbreviations: SES=socioeconomic status, T=tumor, N=lymph node, RT=radiation therapy.