Table 2.
Agreement between metabolic tumor volume and pathology volume.
| PET volume | Number of patients – n (%) |
||||
|---|---|---|---|---|---|
| MTV underestimates pathology volume |
Agree within 2mm | MTV overestimates pathology volume |
|||
| >5mm | 2–5mm | 2–5mm | >5mm | ||
| Absolute SUV thresholds | |||||
| MTV2.0 | 0 (0) | 0 (0) | 3 (13) | 13 (57) | 7 (30) |
| MTV3.0 | 0 (0) | 2 (9) | 7 (30) | 8 (35) | 6 (26) |
| MTV4.0 | 1 (4) | 1 (4) | 13 (57) | 5 (22) | 3 (13) |
| MTV5.0 | 2 (9) | 1 (4) | 13 (57) | 7 (30) | 0 (0) |
| MTV6.0 | 2 (9) | 5 (22) | 10 (43) | 6 (26) | 0 (0) |
| Relative SUV thresholds | |||||
| MTV30% | 0 (0) | 1 (4) | 9 (39) | 12 (52) | 1 (4) |
| MTV40% | 1 (4) | 2 (9) | 12 (52) | 7 (30) | 1 (4) |
| MTV50% | 1 (4) | 5 (22) | 14 (61) | 2 (9) | 1 (4) |
| MTV60% | 3 (13) | 8 (35) | 11 (48) | 1 (4) | 0 (0) |
| MTV70% | 3 (13) | 9 (39) | 10 (43) | 1 (4) | 0 (0) |
| Gradient-based | |||||
| MTVgradient | 1 (4) | 5 (22) | 14 (61) | 3 (13) | 0 (0) |
| Tumor grade | |||||
| MTVtumor grade | 0 (0) | 4 (17) | 16 (70) | 3 (13) | 0 (0) |
This table represents the circumferential marginal difference between PET volume and pathology volume, which was defined as the circumferential distance in millimeters required to expand or shrink the metabolic tumor volume (MTV) such that the MTV and pathology volumes were equal (see Methods for details).