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. Author manuscript; available in PMC: 2012 Oct 1.
Published in final edited form as: J Immunol. 2011 Sep 2;187(7):3831–3839. doi: 10.4049/jimmunol.1003238

Figure 4.

Figure 4

CBLB502 given prior to imposition of renal ischemia attenuates neutrophil but not macrophage infiltration into ischemic kidneys during reperfusion. Groups of 5 C57BL/6 mice were given PBS or 0.5 μg CBLB502 i.v. 30 minutes prior to imposition of bilateral renal pedicle occlusion for 45 minutes. (a) Kidneys were harvested 24 hours after reperfusion from each animal, were digested, and the infiltrating leukocyte populations were quantitated following antibody staining and flow cytometry analyses to detect neutrophils, macrophages, CD4 T cells and CD8 T cells. (b) Kidneys were harvested 9 and 24 hours after reperfusion and prepared tissue homogenates were tested for levels of myeloperoxidase protein. *P < 0.05