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Effect of CBLB502 given prior to imposition of renal ischemia on expression of acute phase cytokines during reperfusion. Groups of 5 C57BL/6 mice were given PBS or 0.5μg CBLB502 i.v. 30 minutes prior to imposition of bilateral renal pedicle occlusion for 45 minutes. Whole cell RNA was isolated from individual kidneys 1, 9 and 24 hours post-reperfusion and tested by qRT/PCR for expression levels of the acute phase cytokines TNFα, IL-1βand IL-6. *P < 0.05.
