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. Author manuscript; available in PMC: 2012 Oct 1.
Published in final edited form as: J Immunol. 2011 Sep 7;187(7):3663–3670. doi: 10.4049/jimmunol.1100103

Figure 3. PGE2 treatment impairs the T cell receptor stop signal.

Figure 3

A) DIC images of HPBT cells migrating on ICAM-1 in the presence or absence of PGE2 (5 μM) and OKT3 (1 μg/mL) demonstrated that OKT3 induced a loss of cell polarity that is abrogated in the presence of both PGE2 and OKT3. Bar, 20 microns. B) Displacement of individual cells during a 15 minute time period. C) Migration speeds in (microns/minute) expressed as mean +/- SEM (n=3, * p < 0.05, ANOVA).