Table 4.
Phenotype | Genotype distribution | MAF | Allelic OR (0.95% CI) | P valuea | P permb |
---|---|---|---|---|---|
SNP: rs34037914 | |||||
TT/TC/CC | |||||
Size of adenoma | 1.44 (0.42–5.00) | 0.56 | 0.62 | ||
Micro | 0/4/13 | 0.11 | |||
Macro | 2/6/23 | 0.16 | |||
Effect of SA on tumor size | NA | 0.014 | 0.02 | ||
Reduced | 0/0/11 | 0 | |||
Enlarged | 2/7/15 | 0.22 | |||
IGF1 after treatment | 3.27 (0.64–16.54) | 0.13 | 0.17 | ||
Below ULN | 0/2/11 | 0.07 | |||
Above ULN | 2/5/14 | 0.21 | |||
Number of adenoma resections | NC | NA | 0.0001c | NC | |
0 | 0/4/16 | ||||
1 | 0/5/18 | ||||
2–3 | 2/1/1 | ||||
SNP: rs642249 | |||||
AA/AG/GG | |||||
Size of adenoma | 1.03 (0.28–3.82) | 0.63 | 0.68 | ||
Micro | 2/4/11 | 0.19 | |||
Macro | 2/8/21 | 0.24 | |||
Effect of SA on tumor size | 0.78 (0.28–2.15) | 0.96 | 0.96 | ||
Reduced | 1/2/8 | 0.19 | |||
Enlarged | 2/5/17 | 0.18 | |||
IGF1 after treatment | 1.04 (0.33–3.31) | 0.94 | 0.95 | ||
Below ULN | 2/2/9 | ||||
Above ULN | 1/8/12 | 0.24 | |||
Number of adenoma resections | NC | NC | 0.5c | NC | |
0 | 2/6/12 | ||||
1 | 2/6/15 | ||||
2–3 | 0/0/4 |
OR, odds ratio; CI, confidence interval; MAF, minor allele frequency; NA, not applicable; NC, not calculated. Association results with P<0.05 are marked in bold.
P value from Fisher exact test.
P value obtained from 100 000 permutation.
P value from Pearson χ2 calculation using 3×3 table (4 degrees of freedom).