Table 5.
Phenotypes (mean±s.e.m.) | |||
---|---|---|---|
Genotype | BMI (kg/m2) | Age at diagnosis (y) | IGF1 % ULN |
SNP: rs34037914 | |||
CC | 28.87±0.80 | 50.43±2.03 | 45.40±14.61 |
CT | 31.35±2.00 | 40.60±3.90 | 63.23±30.03 |
TT | 40.48±1.03 | 28.50±7.50 | 80.23±32.28 |
P valuea | 0.004 | 0.002 | 0.41 |
P permb | 0.012 | 0.006 | 0.81 |
SNP: rs642249 | |||
GG | 31.04±1.06 | 27.19±1.29 | 28.33±0.98 |
GA | 48.25±2.33 | 46.00±3.68 | 44.50±8.85 |
AA | 40.72±16.08 | 88.52±19.92 | 19.93±23.53 |
P valuea | 0.09 | 0.51 | 0.23 |
P permb | 0.23 | 0.87 | 0.97 |
IGF1 % ULN, normalized percentage of ULN ((CIGF1−ULNIGF1)/ULNIGF1×100). Association results with P<0.05 are marked in bold.
P value from linear regression.
P value obtained from 100 000 permutation.