Figure 2.

Photomicrograph of paraffin-embedded rat liver sections stained with hematoxylin and eosin. (a) Liver section of a normal control rat liver showing normal architecture with no cellular degeneration and necrosis. (b) Liver sections of CCl₄ treated rat showing fatty changes, necrosis, cellular degeneration and sinusoidal dilation. (c) Liver section of silymarin + CCl₄ treated rat showing preservation of cellular structure with few coagulating necrosis. (d) CSE 100 mg/kg + CCl₄ treated rat liver sections showing hydrophobic and fatty changes with diffused necrosis. (e) CSE 200 mg/kg + CCl₄ treated rat liver sections showing cellular degeneration, diffused necrosis with lymphocyte infiltration. (f) CSE 300 mg/kg + CCl₄ treated rat liver sections showing well-brought central vein and sinusoid with slight cellular degeneration and coagulative necrosis (CD: cellular degeneration; N: necrosis; CN: coagulating necrosis; DN: diffused necrosis; SD: sinusoidal dilation; HC: hydrophobic changes; FC: fatty changes or steatosis; IL: infiltration of lymphocytes)