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. 2011 Jul 28;12(8):4819–4835. doi: 10.3390/ijms12084819

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© 2011 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

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Figure 6. — Time Course of Skin Whitening Index (L value) of Mice Treated with Vaseline only (control, •), 2% HQ (○), 0.2% RK (▾) or 2% RK (▵) in Vaseline. A total of thirty-two mice were equally divided into four groups and each group was smeared twice daily in 5 consecutive days a week for 3 weeks with 0.1 g Vaseline (control, ), 2% HQ in Vaseline ( ), 0.2% RK ( ) or 2% RK in Vaseline ( ). The L value was measured once a day on the same skin area with a Chromameter CR-2300d. Averaged L values (n = 8) with an error bar of SD are plotted over the experimental period. A value of p < 0.01 by Student’s t-test by comparing the data with that of control at the same time was considered statistically significant.

Inline graphic — Time Course of Skin Whitening Index (L value) of Mice Treated with Vaseline only (control, •), 2% HQ (○), 0.2% RK (▾) or 2% RK (▵) in Vaseline. A total of thirty-two mice were equally divided into four groups and each group was smeared twice daily in 5 consecutive days a week for 3 weeks with 0.1 g Vaseline (control, ), 2% HQ in Vaseline ( ), 0.2% RK ( ) or 2% RK in Vaseline ( ). The L value was measured once a day on the same skin area with a Chromameter CR-2300d. Averaged L values (n = 8) with an error bar of SD are plotted over the experimental period. A value of p < 0.01 by Student’s t-test by comparing the data with that of control at the same time was considered statistically significant.