Figure 1.

Silibinin inhibits proliferation of AsPC-1 (A), Panc-1 (B) and BxPC-3 (C) cells. Cells were plated at a density of 5000 cells per well and then treated with 2‰ (v/v) DMSO (Control) or with different doses of Silibinin (12.5, 25, 50, 100, 200, 400 and 800 μM) for 24, 48 and 72 h. Cell viability was then determined by a MTT assay. Significance was determined by a Student’s t-test (p < 0.05, compared with control).