Table 1.
Characteristics of Eligible Patients (n = 23)
| Characteristic | No. of Patients |
|---|---|
| Sex | |
| Male | 10 |
| Female | 13 |
| Age, years | |
| Median | 8.1 |
| Range | 2.6-17.7 |
| Diagnosis | |
| Ependymoma | 8 |
| Brain stem glioma | 6 |
| Medulloblastoma/primitive neuroectodermal tumor | 4 |
| Glioblastoma multiforme | 2 |
| Malignant glioma (grade III to IV) | 1 |
| Choroid plexus carcinoma | 1 |
| Atypical teratoid/rhabdoid tumor | 1 |
| Prior therapy | |
| Radiotherapy only | 3 |
| Chemotherapy and radiotherapy | 18 |
| Chemotherapy, radiotherapy, and stem-cell transplantation | 2 |
| Courses of MK-0752 | |
| Median | 1 |
| Range | 1-4 |