Table 3.
All Toxicities Attributed to Therapy in Eligible Patients
| Toxicity | Grade |
|||||||
|---|---|---|---|---|---|---|---|---|
| 1 |
2 |
3 |
Total |
|||||
| No. | % | No. | % | No. | % | No. | % | |
| Lymphopenia | 6 | 5 | 7 | 4 | 2 | 1 | 15 | 6 |
| Fatigue | 5 | 5 | 6 | 6 | 11 | 8 | ||
| Hypokalemia | 7 | 5 | 2 | 2 | 9 | 6 | ||
| Increased ALT | 3 | 3 | 2 | 2 | 3 | 3 | 8 | 6 |
| Nausea | 5 | 5 | 1 | 1 | 7 | 7 | ||
| Increased AST | 4 | 4 | 2 | 2 | 6 | 4 | ||
| Hypophosphatemia | 4 | 3 | 1 | 1 | 5 | 4 | ||
| Vomiting | 4 | 4 | 1 | 1 | 5 | 4 | ||
| Leukopenia | 5 | 4 | 5 | 4 | ||||
| Anorexia | 2 | 2 | 1 | 1 | 3 | 3 | ||
| Pain (headache) | 2 | 2 | 1 | 1 | 3 | 3 | ||
| Hyponatremia | 3 | 2 | 3 | 2 | ||||
| Constipation | 3 | 3 | 3 | 3 | ||||
| Neutropenia | 1 | 1 | 1 | 1 | 2 | 2 | ||
| Low serum bicarbonate | 2 | 1 | 2 | 1 | ||||
| Alkaline phosphatase | 2 | 2 | 2 | 2 | ||||
| Diarrhea | 2 | 2 | 2 | 2 | ||||
| Pain | 2 | 2 | 1 | 1 | 3 | 3 | ||
| Thrombocytopenia | 2 | 2 | 2 | 2 | ||||
| Weight loss | 2 | 2 | 2 | 2 | ||||
| Pruritus/itching | 1 | 1 | 1 | 1 | ||||
| Rash/desquamation | 1 | 1 | 1 | 1 | ||||
| Blurred vision | 1 | 1 | 1 | 1 | ||||
| Hypoalbuminemia | 1 | 1 | 1 | 1 | ||||
| Hyperbilirubinemia | 1 | 1 | 1 | 1 | ||||
| Cough | 1 | 1 | 1 | 1 | ||||
| Fever (in the absence of neutropenia) | 1 | 1 | 1 | 1 | ||||
| Hypermagnesemia | 1 | 1 | 1 | 1 | ||||
| Hypomagnesemia | 1 | 1 | 1 | 1 | ||||