Table 2.
Subjects' Anthropomorphic, Laboratory, and Dietary Characteristics
Characteristics | Screening | Study 1 | Study 2 | Study 3 |
---|---|---|---|---|
Anthropomorphic characteristics | ||||
Age, years | 58 ± 7 | — | — | — |
Race | 17 Caucasian | — | — | — |
2 Black | ||||
2 Hispanic | ||||
Body mass index, kg/m2 | — | 29 ± 5 | 29 ± 5 | 29 ± 5 |
Laboratory characteristics | ||||
25(OH)D, ng/mL | — | 28 ± 13 | 36 ± 18 | 35 ± 16 |
1,25(OH)2D3, pg/dL | — | 47 ± 26 | 53 ± 24 | 60 ±18 |
PTH, pg/mL | — | 49 ± 24 | 50 ± 22 | 49 ± 20 |
Serum calcium, mg/dL | — | 9.1 ± 0.4 | 9.2 ± 0.3 | 9.2 ± 0.4 |
Serum creatinine, mg/dL | — | 0.8 ± 0.1 | 0.8 ± 0.1 | 0.8 ± 0.1 |
Urine calcium, mg/24 h | — | 153 ± 67 | 152 ± 64 | 146 ± 46 |
Dietary habits | ||||
Kilocaloriesa | 2200 ± 340 | 2100 ± 310 | 2100 ± 320 | 2100 ± 300 |
Calcium, mg | 1400 ± 650 | 1400 ± 650 | 1400 ± 650 | 1400 ± 650 |
Carbohydrates, gb | 270 ± 60 | 250 ± 50 | 250 ± 50 | 250 ± 50 |
Protein, g | 88 ± 21 | 84 ± 20 | 83 ± 20 | 83 ± 20 |
Fat, g | 87 ± 22 | 85 ± 22 | 85 ± 23 | 85 ± 23 |
Fiber, g | 24 ± 11 | 23 ± 10 | 22 ± 9 | 23 ± 10 |
Vitamin D, IUc | 160 ± 100 | 150 ± 100 | 150 ± 100 | 150 ± 100 |
Sodium, mga | 3400 ± 890 | 3300 ± 820 | 3300 ± 810 | 3300 ± 820 |
Magnesium, mg | 360 ± 110 | 360 ± 120 | 360 ± 110 | 360 ± 110 |
Iron, mg | 16 ± 5 | 16 ± 6 | 16 ± 6 | 16 ± 6 |
Caffeine, mg | 170 ± 150 | 160 ± 110 | 160 ± 110 | 160 ± 110 |
Oxalate, servings | 1.2 ± 1.0 | 1.1 ± 1.0 | 1.2 ± 1 | 1.4 ± 1 |
Note: Fractional calcium absorption studies 1, 2, and 3 occurred at baseline, 39 ± 17 days, and 64 ± 2 days later, respectively. We used analysis of variance with a Bonferroni correction to compare within-subject changes in laboratory characteristics and dietary habits during study visits. Four dietary parameters were statistically different during inpatient visits compared with subjects' usual dietary intake based on 7-day diet diaries secondary to incomplete meal consumption.
p < .0001.
p = .0015.
p = .005.